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Although m184iv may reduce the genetic barrier of ddi for mutations such as k65r and l74v, the lack of reemergence of m184iv in the minor quasispecies of most patients. Deep sequencing analysis of m184vi mutation at the switch and, The m184v mutation in hiv1 reverse transcriptase reduces the, The m184v mutation in hiv reverse transcriptase rt is associated with highlevel resistance against the nucleoside inhibitor lamivudine as well as diminished viral replication capacity. The m184v mutation in hiv reverse transcriptase rt is associated with highlevel resistance against the nucleoside inhibitor lamivudine as well as diminished viral replication capacity.
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